Investigating neuronal cell types through comparative cellular physiology

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Investigating neuronal cell types through comparative cellular physiology

Comprehensive understanding of nervous systems would require the unambiguous identification of all neuronal cell types, which are distinguished by gene-expression differences, particularly in plasma-membrane receptors and ion channels. Toward this ultimate goal, a recent paper initiated an approach to identify and study divergent neuronal cell types through comparative cellular physiology.

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Neuronal cell types

Identifying the functionally distinct types of neuron is central to any bottom-up understanding of how the brain works. The different cell types are the brain’s elementary computational elements — the components from which the larger machine is made. We have known of some cell types for more than a century, but the coverage has been spotty and anecdotal. This is changing: it is now possible to ...

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Neuronal cell types and taste quality coding.

Over the past 25 years, there have been two opposing views of how taste information is represented in the activity of gustatory neurons. One view, the across-fiber pattern (AFP) theory, postulates that taste quality is represented by the pattern of activity across the afferent population. Stimuli with similar tastes produce similar patterns of activity. The other view is that activity in a few ...

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Reprinted from JOURNAL OF CELLULAR AND COMPARATIVE PHYSIOLOGY

Many of the models of hemopoiesis that have been proposed (see, for example, Cronkite et al., '59) are based on the assumption that the continued production of blood cells requires the presence of progenitor cells with the capacity for continued proliferation. From this point of view, hemopoietic tissue may be considered to consist of two compartments; the first, or stem cell compartment, consi...

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Comparative Physiology

Comparative physiology studies cellular, organ and organismic phenomena. It benefits from the diversity found in the animal kingdom. This diversity results from the enormous number of animal species and also from the size variation found among them. While describing the basic physiological systems in various animal groups it provides important basic information. The study of physiological varia...

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ژورنال

عنوان ژورنال: Temperature

سال: 2014

ISSN: 2332-8940,2332-8959

DOI: 10.4161/temp.29540